ABSTRACT
Objective: To investigate antioxidant activity, total phenolic and flavonoid content of ethanol (E) and ethyl acetate (A) extracts of Inula viscosa aerial parts selected from three regions of Morocco (Imouzzer, Sefrou and Taounate). Methods: Antioxidants properties were measured by three different test systems of assay namely free radical scavenging activities against 2,2-diphenyl-1-picrylhydrazyl, total antioxidant capacity and iron-reducing capacity. Total phenolic content was measured by Folin- Ciocalteu reagent. Results: All the extracts showed significant antioxidant activities and contained important levels of phenols. The ethanol extract (0.3 mg/mL) from Sefrou showed the greatest antioxidant capacity in the three systems of assay, which was probably due to its high content of polyphenols (274.39±6.94) mg gallic acid equivalent/g dry extract. Total flavonoid content was found equal for all extracts. Conclusions: Our results of antioxidant assays were justified and partially supported the popular usage of the tested plants. The high antioxidant activity found in the plant from Sefrou and its great biomass in this region suggested that Inula viscosa is a good source of natural antioxidants compounds which might have benefits for health.